BY Tatiana Siegel

{Variety} - Amy Adams is in negotiations to star opposite Ben Stiller in 20th Century Fox's "Night at the Museum 2."

Pic kicks off when the artifacts from the Museum of Natural History are boxed up and sent to the archives at the Smithsonian in Washington. Adams will play an undetermined historical figure who has a crush on security guard Larry (Stiller).

Shawn Levy returns to helm the sequel, which has a U.S. release date set for May 22, 2009. Robert Ben Garant and Thomas Lennon penned the screenplay, Scott Frank the most recent draft.

Levy's 21 Laps is producing alongside 1492 Pictures. Michael Barnathan and Mark Radcliffe will serve as producers. Studio is eyeing a May start date in Vancouver.

Adams is onscreen in "Charlie Wilson's War" and "Enchanted." She stars in the indie "Sunshine Cleaning," which bowed at the Sundance Film Festival.

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